The world’s first-ever gene therapy clinical trial in patients with advanced Parkinson’s disease significantly reduced their symptoms, suggesting surgery to deliver a modified gene directly to the brain could be a safe new treatment option for a number of neurodegenerative diseases.
Read the full story and view the video.
A study suggests that acute leukemia patients whose cancer cells show a genetic change that usually predicts a swift return of the disease following remission may remain disease-free longer when given aggressive therapy. The findings apply to people with acute myeloid leukemia (AML) whose cancer cells have normal-looking chromosomes and a gene mutation called MLL-PTD.
Read the full story and view the video.
Scientists have identified a potential therapeutic target in muscles for the treatment of Duchenne muscular dystrophy, the most common form of the progressive disease. The study confirmed that a particular protein is responsible for the chronic inflammation and muscle-cell death that are hallmarks of Duchenne muscular dystrophy.
Read the full story and view the video.
A newly instituted screening test performed on all colon cancer patients at the Ohio State University Medical Center’s James Cancer Hospital and Solove Research Institute may be key to detecting a hereditary cancer syndrome that puts people at high risk for tumors of the colon, endometrium, stomach and ovaries.
Read the full story and view the video.
Web sites that use family medical history to help estimate a person’s risk of developing cancer should be improved to reach a more diverse audience and should take a more comprehensive view of family cancer history, according to a recent study by Ohio State University cancer researchers.
Read the full story and view the video.
On the surface, the two women, both in their early 60s, appeared to have the same disease: early stage, estrogen receptor positive breast cancer, and until recently, they probably would have received the same treatment. But oncologists are increasingly using a new gene assay that helps predict how aggressive a tumor really is – and how likely it is the cancer will recur.
Read the full story and view the video.